The Nobel Prize in Chemistry this year goes to Stefan Hell in Göttingen and Eric Betzig and William Moerner (both United States). This was announced by the Royal Swedish Academy of Sciences on Wednesday in Stockholm. Hell is Director at the Max-Planck-Institute for Biophysical Chemistry in Göttingen.
The three scientists received the award for her research in the so-called nanoscopy. It is used to represent individual molecules in living cells. The researchers, for example, reflect how molecules form synapses between nerve cells in the brain. Or they can show proteins that play a role in diseases such as Parkinson’s or Alzheimer’s. Nor can observe individual proteins, which develop in fertilized eggs to embryos.
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The fact that researchers ever be able to examine living cells even in the smallest molecular detail, in science for a long time was anything but clear. Even in 1873 claimed the German physicist Ernst Abbe that the optical resolution of traditional optical microscopes is limited to 0.2 microns. Betzig, Hell and Moerner received the Nobel Prize for it now, “this limit to have overcome,” said the Nobel committee. The three scientists was thanks to that now take a look at the nano world is possible.
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The German researcher Stefan Hell have developed the method of the so-called STED microscopy, said the Nobel committee. STED stands for “Stimulated Emission Depletion”. In this case, two different laser beams are used. One of them excites the molecules of an examined specimen, so that they radiate a special light. Another beam filtered out of this emitted light nanoparticles. This method is a particularly high resolution in microscopy possible.
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Betzig and Moerner developed the so-called single-molecule microscopy. This method makes use of the fact that it is possible, the optical emission of single molecules on or turn off. Researchers consider doing the same area several times, always only certain molecules are brought to “glow”. This method allow particularly dense pictures at the nano level, so the committee. Eric Betzig’ve first used in 2006.
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